Immunology Interview Preparation Guide Download PDF
Immunology Interview Questions and Answers will guide us now that Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. Immunology deals with, among other things, the physiological functioning of the immune system in states of both health and disease. Learn conceptual Immunology or get preparation of Immunology jobs interview by our this Immunology Interview Questions and Answers Guide.
200 Immunology Questions and Answers:
Table of Contents
1 :: Give the classification of hypersensitivity?
Hypersensitivity is classified into five types-
► 1. Anaphylaxis
► 2. Antibody dependant cytotoxicity
► 3. Immune complex mediated diseases
► 4. Delayed type ‘o’ cell mediated hypersensitivity
► 5. Stimulatory hypersensitivity
► 1. Anaphylaxis
► 2. Antibody dependant cytotoxicity
► 3. Immune complex mediated diseases
► 4. Delayed type ‘o’ cell mediated hypersensitivity
► 5. Stimulatory hypersensitivity
2 :: What is anaphylaxis?
It is most rapid hypersensitive reaction. It responds within minutes of applying a stimulus and can get localize. Reactions are mediated by release of pharmacologically active substances.
3 :: What is hypersensitivity?
The inflammatory response produced by inflammatory molecules result in tissue damage and some times even death. We call this as hypersensitivity or allergy.
4 :: What is delayed hypersensitivity?
We can recognize the Symptoms only days after exposure. This is delayed hypersensitivity (DTH).
5 :: What is a myeloma protein?
It is a monoclonal immunoglobulin produced from a myeloma cell.
6 :: What is opsonin?
Opsonin is a substance, which promotes phagocytosis of antigens by binding to them.
7 :: What is an incomplete antibody?
Antibody can bind to an antigen but cannot induce agglutination is called incomplete antibody.
8 :: What are iccosomes?
The particles coated with immune complexes and are released from follicular dendritic cell extensions, are called as iccosomes.
9 :: Name the scientists who classified hypersensitivity.
Coombs and Gell
10 :: What are hypersensitive reactions?
If humoral or cellular immunity is switch on to high for length of time, tissue damage may occur. Such reactions are called hypersensitive reactions.
11 :: What is auto immunity?
Disease caused by immunological reaction to self-antigen. Such type of diseases is classified either organ specific or non-organ specific.
12 :: Name some of the immuno suppressive agents.
► Cytotoxic agents such as chlorambucil, cyclophosphamide, and azathioprine
► Glucocorticoids
► Cyclosporine
► Antilymphocyte antibodies
► Glucocorticoids
► Cyclosporine
► Antilymphocyte antibodies
13 :: What is immuno suppression?
Immuno suppression is particularly given to the patients who are undergoing organ transplantation in the treatment of autoimmunity, graft rejection and in allergy conditions.
14 :: What are the types in adjuvants?
► 1. Organic adjuvants
► 2. Synthetic adjuvants
► 3. Tuftsin
► 2. Synthetic adjuvants
► 3. Tuftsin
15 :: What is an adjuvant?
Adjuvant potentates the immune response Vaccines need to be enhanced by some substances, these substances are called adjuvants.
16 :: What is vaccination?
Vaccination means exploiting the immune system to protect against infectious diseases. Vaccination is done to protect against lethal diseases such as mumps, rubella, poliomyelitis, diphtheria, tetanus, small pox etc.
17 :: What is attenuation?
Natural behavior of an organism without causing disease is called attenuation i.e. reducing pathogenesity of the organism.
18 :: What is secondary immune response?
Secondary immune response occurs when second exposure to the same antigen occurs after weeks, months or after years.
19 :: What is inductive or latent period?
After immunogen is introduced no antibody is detected, this is latent or inductive period. In this period, immunogen is recognized as a foreign substance.
20 :: What is primary immune response?
First exposure to an antigen produces primary immune response.
21 :: What is a binder?
The binding protein (usually antibody) which binds to the ligand is called as binder.
22 :: What is an analyte or ligand?
The substance whose concentration is to be determined is called as an analyte or ligand.
23 :: What is importance of radio immuno assay?
It is the most sensitive technique used for detecting antigen or antibody. This type of reaction is also called as binder ligand assay.
24 :: In radio immuno assay what is the used to label an antigen?
In this technique, the antigen is generally labeled with a- emitting isotopes such as I125.
25 :: What is radio immuno assay?
It is a competitive binding assay in which fixed amount of antibody and radiolabelled antigen react in the presence of unlabelled antigen.